The health ministry said 4,313 people who tested positive for the virus in hospital had died as of 1600 GMT Friday while there were 41,903 confirmed cases as of 0800 GMT Saturday, up 3,735.
House Speaker Nancy Pelosi said another $1 trillion is needed, beyond the just-passed $2.2 trillion effort. She wants another round of direct payments to Americans and more money for companies to keep making payroll.
The beginning of vaccinations could be a crucial shift in the battle against a virus that has claimed more than 1.4 million lives worldwide, including 255,000 just in the US, since emerging from China late last year.
Pfizer Chairman and CEO Albert Bourla called the development "a great day for science and humanity." Health experts said Pfizer's results show vaccines can halt pandemic.
US President Donald Trump pledged to "crush" the coronavirus pandemic with a vaccine by the end of the year, as he accepted the Republican nomination for a second term.
The move comes amid growing concerns of cutbacks and closures of news organisations hit by lockdowns and a massive slump in advertising resulting from the health crisis.
This is one of the most dangerous and idiotic suggestions made so far in how one might actually treat COVID-19," said Paul Hunter, a professor of medicine at Britain's University of East Anglia. He said infecting disinfectants would be likely to kill anyone who tried it.