The deaths on Friday came as thousands of Palestinians held protests at several sections of the Israel-Gaza border fence. Gaza's health ministry said 38 others were wounded by live fire.
The ministry said another Palestinian was hospitalised in the shooting that came after the Israeli army said an attack helicopter and tank had fired at "armed suspects" along the barrier that separates Israel from Gaza.
Palestinian media said Samoudi was wounded while standing at her window as Israeli troops were firing tear gas and gunshots during a confrontation with residents of the city's Jaberyat neighborhood during the raid.
Israeli forces opened fire on four Palestinians near the Gaza border fence on Saturday, killing the men, the Israeli military said.
"The killing of young people on the borders of the Gaza Strip is a continuation of the (Israeli) occupation's crimes everywhere, in the West Bank and Jerusalem," Hamas spokesman Hazem Qasem sa
Palestinians in the Gaza Strip are preparing to mark the beginning of the Islamic holy month of Ramzan from Friday amid a deteriorating economic situation due to the COVID-19 pandemic.
When an Israeli air strike targeted a security office near her home in Gaza this month, 10-year-old Zeina Dabous frantically scribbled a note and slipped it under her mother's pillow.
Empathy in the world had ceased to exist before the ceasefire in Gaza was announced.
Supporters of Muna and Mohammed Al Kurd, who are twins, say their detention is part of a broader Israeli effort to halt opposition to the evictions in Sheikh Jarrah, where Jewish settlers want to move into the Al Kurds' home and others under an Israeli court ruling.
The Associated Press said on Saturday it was "shocked and horrified" by an Israeli airstrike that destroyed a building housing the US news agency's Gaza bureau and those of other international news media. The White House said it has cautioned Israel about the importance of protecting independent media.