A protester waves the national flag during clashes with security forces in central Baghdad. Hadi Mizban/AP

Six Iraqis including two police officers were killed and scores were wounded in Baghdad and other cities on Monday in clashes with security forces, medical and security sources said, as anti-government unrest resumed after a lull of several weeks.

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Three Katyusha rockets fell inside the capital's heavily fortified Green Zone which houses government buildings and foreign missions, police sources told the media.

The rockets were launched from Zafaraniyah district outside Baghdad, the sources said, adding that two rockets landed near the US embassy.

Security forces fire tear gas to disperse anti-government protesters during clashes in Baghdad. AP

Three protesters succumbed to their wounds at a Baghdad hospital after police fired live rounds in Tayaran Square, the sources said. Two protesters were shot by live bullets while a third was hit by a tear gas canister, they said.

A fourth demonstrator was shot dead by police in the Shi'ite holy city of Kerbala, the sources added.

The violence was the latest since protests in Iraq reignited last week after a brief lull amid soaring tensions between Washington and Tehran following a U.S. drone strike that killed top Iranian general Qassem Soleimani in Baghdad earlier this month.

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Protesters threw petrol bombs and stones at police who responded with tear gas and stun grenades, Reuters witnesses said.

“They (security forces) should stop shooting and aiming, who are they and who are we? Both sides are Iraqis. So why are you killing your brothers?” said one woman protester in Baghdad who declined to give her name.

Security forces try to disperse anti-government protesters during clashes in Baghdad. AP

In the Iraqi oil city of Basra, two policemen were struck and killed by a civilian car during a protest, security sources said. The driver was trying to avoid the scene of clashes between protesters and security forces when he drove into the two officers, they said.

Elsewhere in southern Iraq, hundreds of protesters burned tyres and blocked main roads in several cities, including Nassiriya, Kerbala and Amara. They say Prime Minister Adel Abdul Mahdi has not fulfilled promises including naming a new government acceptable to Iraqis.

Baghdad police said its forces had reopened all roads that were closed by "violent gatherings". It said 14 officers were wounded near Tahrir square, including some with head wounds and broken bones.

Security forces crack down on demonstrators as traffic is hit on a highway. Hadi Mizban/AP

Traffic was disrupted on a highway linking Baghdad to southern cities, a Reuters witness said. Production in southern oilfields was unaffected by the unrest, oil officials said.

Mass protests have gripped Iraq since Oct. 1, with mostly young protesters demanding an overhaul of a political system they see as profoundly corrupt and as keeping most Iraqis in poverty. More than 450 people have been killed.

Numbers had dwindled but protests resumed last week as demonstrators sought to keep up momentum after attention turned to the threat of a US-Iran conflict following Washington's killing of Tehran's top general in an air strike inside Iraq.

The killing of Qassem Soleimani, to which Tehran responded with a ballistic missile attack on two Iraqi military bases housing US troops, has highlighted the influence of some foreign powers in Iraq, especially Iran and the United States.