While Kieron Pollard played his last T20 in India last November, Sunil Narine’s last appearance in a T20 came against England almost two years ago.
The Caribbean side scored 311 for six in their 50 overs in Leeds and although the Afghans put up a brave fight, they ultimately went down by 23 runs.
Only 7.3 overs were bowled at Hampshire's Rose Bowl on Monday after West Indies skipper Jason Holder won the toss and sent South Africa in to bat.
The two-time champions, who are unbeaten in their six outings so far, including a washed-out game, fielded an unchanged side after their narrow victory against Afghanistan.
England were held up by a last wicket stand of 99 between Keshav Maharaj (71) and Dane Paterson (39 not out) and it needed a direct-hit run-out by Sam Curran from mid-on to clinch the result shortly before lunch. South Africa were bowled out for 237.
The ageless Swiss great, 38, said ahead of the tournament that he had low expectations at the year's opening Grand Slam after missing the warm-up ATP Cup to spend more time with his family.
Lee Westwood defied the age and shot a stunning round of 67 (-5) to claim the 15th edition of the Abu Dhabi Golf Championship by two strokes, taking his tally of European Tour