Set a daunting 370-run target, South Africa finished the fourth day on 127-1 with Markram on 59 and Dussen unbeaten on 48. The tourists will need another 243 runs to level the series on Monday. Rizwan's masterclass helped Pakistan add 169 runs for the loss of four wickets in the day before being bowled out for 298.
South Africa need 19 runs to win off the last over, but medium pacer Faheem Ashraf held his nerves to keep the visitors down to 166-6 while Bjorn Fortuin (17 not out) and Dwaine Pretorius (15 not out) could manage only 15.
Tail-ender Hasan Ali finished with a seven-ball 20 not out as Pakistan overhauled a 165-run target in 18.4 overs to win the series 2-1, South Africa's first T20I series defeat in Asia. South Africa had previously won five and drawn one T20I series in Asia.
The Multan Sultans cruised to victory courtesy Mohammad Rizwan and Sohaib Maqsood's flashy 110-run, third wicket partnership. Earlier, Lahore Qalandars had set a target of 158 for the Multan Sultans courtesy Mohammad Hafeez's 60 off 30 balls.
Babar’s unbeaten 90 off 60 balls — including 13 fours and a six — led Karachi to 198-3 with seven balls to spare in yet another successful chase in Pakistan’s premier Twenty20 league.
The Pakistan cricket team will depart on Nov.23 for Lincoln, New Zealand, where they will spend two weeks in quarantine. T20 internationals are scheduled for Auckland on Dec.18, Hamilton on Dec.20 and Napier on Dec.22.
The first Test is at Mount Maunganui from Dec.26-30, with the second at Christchurch from Jan.3-7.
Iftikhar Ahmed spun a web around Zimbabwe's batsmen with figures of 5-40 to wreck them for a paltry 206 before Azam knocked an attractive 74-ball 77 not out to chase down the target in 35.2 overs.
Aleem Dar has been awarded a special memento for his 210th appearance when he turned up for the second ODI match between Pakistan and Zimbabwe.
Azam proved yet again why he is one of the top batsmen in white-ball cricket with an attractive 55-ball 82 to anchor Pakistan's chase of a modest 157-run target in 18.5 overs.