Grand marshal Sandra Lindsay, a health care worker who was the first person in the country to get a COVID-19 vaccine shot, waves to spectators as she leads marchers through the Financial District, in New York. File/Associated Press

Michael Hiltzik, Tribune News Service

One year ago, we were looking forward to a safer and sounder 2021. The Food and Drug Administration had granted emergency authorization to the Pfizer-BioNTech and Moderna vaccines against COVID-19.

A new presidential administration was poised to take office in the next month, armed with a commitment to bring together a nation cleaved by four years of divisive policymaking.

It was not to be. Instead of unity and immunity, this year has brought us stupidity and insanity on an unimaginable scale. In the categories of public health, education policy, fiscal policy and investment options, we appear to have taken leave of our collective senses.

Certainly there are other years or periods in which stupidity or heedlessness brought civilisation in general close to eradication.

Consider 1914, when most of Europe dived hellbent to war for no discernible reason. (Read Barbara Tuchman’s book “The Guns of August” for the full horrific picture.) The Dark Ages were a period benighted by scientific ignorance.

Some individual countries and national leaders stand out for tempting fate, to their and their citizens’ misfortune. Britain in 1938 under Neville Chamberlain. Russia’s warmongering with Japan in 1904-1905. Louis Napoleon poking a stick into the Prussian bear’s cage in 1870-1871. Saddam Hussein invading Kuwait in 1990.

The perpetrators of some of these errors might assert in their defense that they were brought low by circumstances they didn’t know at the time.

But America in 2021 can’t plead that it didn’t know. Didn’t know that vaccines representing stupendous scientific achievements were the solution to the COVID-19 pandemic?

Didn’t know that Donald Trump wasn’t joking when he demanded that government officials overturn a fair presidential election? Didn’t know that bitcoin, NFTs, SPACs and meme stocks were destined, even designed, to take unwary investors to the cleaners?

Of course we knew, and know. We don’t seem to care.

In reviewing the most intellectually demoralising events of 2021, I’ll leave aside a few discrete outbursts of asininity. So I won’t go into detail about the conservative movement’s lionizing of Kyle Rittenhouse, the self-confessed but acquitted killer of two unarmed men at a protest rally in Kenosha, Wis. Or the openly antisemitic ravings by former President Trump. Or the ugly, dishonest attacks that forced the withdrawal of Saule Omarova, one of the most qualified nominees for a federal banking regulatory job in memory.

Or the shameful behaviour of congressional Republicans, who cowered in safety during the Jan. 6 insurrection, pleading with Trump to help quell the riot, only to claim ever since that the violence of the crowd was no big deal.

Or the posting of Christmas cards by politicians showing their families hoisting assault weapons, as Rep. Thomas Massie (R-Ky.) did just four days after a gunman killed four students at a Michigan high school. He was followed by Rep. Lauren Boebert (R-Colo.).

Instead, we’ll focus on a few of the bigger pictures. So, as Virgil said to Dante before guiding him into the Inferno, “Let us descend now into the blind world.”

COVID-19: The pandemic is surely the focus of the most obtuse and ignorant public reactions and state and local policy responses to any crisis in American history. It’s as if the grown-ups have all been beamed up, and we are left in the hands of people like Florida Gov. Ron DeSantis. (I am paraphrasing a line from the great pandemic movie “Together.”)

In any rational world, the refusal or failure by some 50 million adult Americans to take a vaccine of known efficacy against a deadly disease would be inexplicable. But this is not a rational world, and the situation is even worse.

Vaccine refusal is seen in many benighted corners of the United States not merely as the exercise of personal choice for personal reasons but as a means of showing moral superiority over the vaccinated.

A conservative critic of anti-pandemic measures writing from rural southwest Michigan for the Atlantic bragged absurdly and selfishly, “I am now closer to most of my fellow Americans than the people, almost absurdly overrepresented in media and elite institutions, who are still genuinely concerned about this virus.” The author may think he’s remote from virus concerns, but that’s not the case at a hospital visited by CNN in Lansing, Mich., which can’t be much more than 100 miles from his location and where “the latest COVID-19 surge is as bad as health care workers there have seen.”

How did it come to pass that Americans, who almost uniformly are inoculated against at least a half-dozen serious diseases in childhood, chose this moment to refuse a spectacularly effective shot against one of the most dangerous diseases to arise in their lifetimes, out of pure ignorance?

Its effectiveness is scarcely disputable: The Commonwealth Fund estimates that the vaccine averted about 1.1 million American deaths from COVID-19 and more than 10.3 million hospitalizations this year.

The answer lies in politics. Trump drew the line first, dismissing social distancing steps and refusing to speak up for vaccination. He established these steps as partisan choices, and his political acolytes followed him over the cliff.

DeSantis has been a leader in this descent into the Inferno. He’s chosen to make Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases and America’s most respected authority on the pandemic, a target of partisan calumny. He’s appointed a vaccine doubter as his state’s top public health official.

What is the outcome? Florida currently ranks eighth-worst among states in its COVID-19 death rate, with more than 62,000 Floridians having perished from the virus. Of the seven states with worse records, six are red states like Florida.

Corporate America has not showered itself in glory. On Dec. 18, Boeing announced that it was dropping its requirement that all US employees be vaccinated. Its explanation was that a federal judge had blocked the enforcement of a federal executive order that employees of government contractors be vaccinated.

This is absurd. Nothing in the ruling required Boeing to drop its requirement. The company announced its step back just as the omicron variant was about to produce a surge in infections. The pusillanimity of American corporations on this subject continues to astound. (The Times, which is owned by a physician and biomedical entrepreneur, is requiring all employees to be fully vaccinated by Jan. 31.)

To its credit, on Dec. 17 the Biden White House issued an uncompromising warning about the dangers of remaining unvaccinated.

“For the unvaccinated, you’re looking at a winter of severe illness and death for yourselves, your families and the hospitals you may soon overwhelm,” White House Chief of Staff Ron Klain said. “So, our message to every American is clear.... Wear a mask in public indoor settings. Get vaccinated, get your kids vaccinated, and get a booster shot when you’re eligible.”