Photographs shared by residents shows a plume of smoke over the area of the blasts.

At least 19 people were killed and 50 others injured in an attack on a military hospital in Kabul on Tuesday, the latest assault to rock Afghanistan since the Taliban seized power.

Two blasts struck close to the entrance of the sprawling site followed by reports of shooting inside the hospital, the Taliban and a witness said.

"Nineteen dead bodies and about 50 wounded people have been taken to hospitals in Kabul," a health ministry official who asked not to be named told AFP.

The Taliban spent 20 years waging an insurgency against the ousted US-backed government.

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Now they face the struggle of bringing stability to Afghanistan, which has been hit in recent weeks by a series of bloody assaults by the Daesh group's local chapter.

Tuesday's attack has not yet been claimed by any group.

"I am inside the hospital. I heard a big explosion coming from the first checkpoint. We were told to go to safe rooms. I also hear guns firing," a doctor at the Sardar Mohammad Daud Khan hospital in Kabul told AFP.