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Nine people were killed and more than 30 were missing in Myagdi district, 200 km (125 miles) northwest of the capital Kathmandu, where several houses were destroyed on Friday, district administrator Gyan Nath Dhakal said.
"The toll is expected to increase as rescuers had just reached the remote site to look for victims," Dhakal said, adding that 50 people had been plucked to safety using helicopters.
In neighbouring Kaski district, seven people were killed, said a second government official in the tourist town of Pokhara.
Another seven were killed in Jajarkot district in the far west.
"We are searching for eight people who are still missing," said Kishore Shrestha, a senior police official.
In the southern plains bordering India, the Koshi river, which causes deadly floods in the eastern Indian state of Bihar almost every year, was flowing above the danger level, police said.
Landslides and flash floods are common occurrence in mountainous Nepal during the June-September monsoon every year.Reuters
The death toll from floods and landslides in India rose to 85 on Wednesday, officials said, while Nepal also reported 43 fatalities and 43 missing.
Experts say that they were victims of the ever-more unpredictable and extreme weather that has hit South Asia in recent years caused by climate change and exacerbated by deforestation, damming and excessive development.
Heavy rains since Thursday have hit several districts in Nepal, especially in the country's eastern region and the southern plains, affecting thousands.
Seven people from the same family, including three children and three women, were killed in their sleep late on Tuesday when their house was swept away in the remote Naraharinath village, 430km (268 miles) northwest of the capital Kathmandu.
Two persons were killed, while one was seriously injured after a vehicle had swerved and crashed into concrete pillar at the entrance of Cleveland Clinic-Abu Dhabi hospital, on Wednesday morning.
Commenting on the incident, the Ministry of Education indicated that the school was not licensed and did not exist in the licensing records, calling on parents to investigate the accuracy when choosing a school to enroll their children in.
Apple said there would be a 'dedicated classical music app' coming this year, with the app combining Primephonic's classical user interface with 'more added features,' reports MacRumor.