People gather at the site of a bomb blast in Quetta on Monday. Reuters
Two police personnel were among those killed in the blast in the city of Quetta, the capital of Balochistan province, which borders Afghanistan and Iran.
"We have received 10 bodies so far and 35 injured in Civil Hospital,” a hospital official said.
Police said the blast went off near Quetta's press club, where dozens of supporters for an Islamic party had gathered outside. They added that police officers were among those killed.
Hospital officials say some of the wounded persons were listed in critical condition.
No one immediately claimed responsibility for the bombing. Baloch separatist groups, as well as rival militants, operate in the province and have staged similar attacks before.
City police chief Abur Razza Cheema said dozens of followers of the Ahl-e-Sunnat Wal Jammat party were rallying to pay tribute to Islam’s first caliph when the bomber blew himself up there.
Footage on social media appeared to show the explosion ripping through the local bazaar, sending people running for shelter.
The bombing destroyed some nearby shops and vehicles, police said.
Local officials said the attack happened after two police were killed at a roadside checkpoint outside the city.
Wreckage of vehicles littered the pavement near the shrine as first responders rushed to the scene and armed security forces fanned out in the area.
"As we crossed the road a blast took place in front of us," witness Ritat Shahid told AFP.
The attack outside the Marshal Fahim National Defense University in western Kabul took place at the road entrance to the war college.
The UAE has strongly condemned the terrorist attack, killing at least eight students and wounding 136 others. It took place on Tuesday in a religious school in the city of Peshawar, northern Pakistan, which claimed the lives of a number of innocent civilians, including children, and wounded others.
Two of those killed were on the train and one was in the truck, Missouri State Highway Patrol spokesman Cpl. Justin Dunn said. Officials were still trying to determine the exact number of people aboard. Seven cars derailed, the patrol said.
The leaders vowed that Russian President Vladimir Putin and those responsible would be held to account for Monday's strike in the city of Kremenchuk, carried out during the shopping mall's busiest hours.
The attacks shattered apartment buildings, video footage showed. The blast gouged a vast crater in front of the school, with debris strewn about classrooms, their windows all blown out.