A man walks past the home of Palestinian commander after it was hit by an Israeli strike. Reuters

An Israeli strike on Damascus on Tuesday hit the home of a leading Palestinian figure, killing his son and one other person, Syrian state news agency SANA and his group said.

Two rockets targeted the home of a senior figure of the Palestinian group, Akram Al Ajouri, "killing his son Muadh and another person", SANA said.

Palestinian shot dead by Israeli forces in West Bank

Israeli forces kill top Palestinian resistance group commander in Gaza strike

An AFP correspondent at the scene of the dawn strike saw a partially destroyed three-storey building in a chic neighbourhood of the capital not far from the Lebanese embassy.

People gather near the home of Palestinian commander after it was hit by an Israeli strike on Tuesday. Reuters

Glass had been blasted from one of the windows.

The group confirmed Ajouri's son had been killed in the attack, which came as a similar strike took the life of an Islamic Jihad commander in Gaza.

"The home of a member of the political bureau of the Islamic Jihad movement in Palestine, Akram Al Ajouri, was also targeted in Damascus, killing one of his sons," it said.

The Israeli army did not immediately respond to a request for comment.

Since civil war erupted in Syria in 2011, Israel has carried out hundreds of strikes in the neighbouring country.

Most have been against what Israel said were Iranian targets or positions of Iran's Lebanese ally, Shiite militant group Hezbollah.