While Kieron Pollard played his last T20 in India last November, Sunil Narine’s last appearance in a T20 came against England almost two years ago.
The Caribbean side scored 311 for six in their 50 overs in Leeds and although the Afghans put up a brave fight, they ultimately went down by 23 runs.
Only 7.3 overs were bowled at Hampshire's Rose Bowl on Monday after West Indies skipper Jason Holder won the toss and sent South Africa in to bat.
The two-time champions, who are unbeaten in their six outings so far, including a washed-out game, fielded an unchanged side after their narrow victory against Afghanistan.
Cross-code star Sonny Bill Williams was benched and fellow centre Ryan Crotty missed out altogether as New Zealand named their team for Saturday’s Rugby World Cup quarter-final against Ireland.
Bottom club Ittihad Kalba will look to bounce back to give their new coach a winning debut when they take on Fujairah in the fourth round match of the Arabian Gulf League (AGL) on Friday.