Art historian Letizia Montalbano analyses 'Il Paesaggio' by Renaissance artist Leonardo Da Vinci.
The museum's research and restoration institute confirmed Da Vinci's ambidexterity by analysing a drawing known simply as Landscape (8P), believed to be his earliest work, dated 1473, when the artist was 21.
The drawing of the Arno river which flows through Florence and the castle of Montelupo in the background also features two handwritten text inscriptions, one on the front written backwards and another on the back written left to right.
Researchers showed that both inscriptions were done by the artist who "used his left hand to write the inscription in 'mirror writing' on the front, while he used his right hand to pen the inscription on the back in ordinary writing," the Uffizi said in a statement.
"Leonardo was born left-handed but he was 're-educated' at a very early age to use the right hand," said art historian Cecilia Frosinini.
"From an observation of his handwriting, including the inscriptions on this drawing, it is clear that his writing as a right-hander was both cultivated and well formed," she said.
"Leonardo was eminently capable of using his right hand... Our hypothesis is that the idea came to him from his observation of the writing in reverse on the tracing paper that he used for his drawings after turning them over."
The research was completed ahead of the drawing's return to Leonardo's birthplace, Vinci, as part of an exhibition to mark 500 years since his death.
French art masterpieces have been renamed after their long overlooked black subjects in a ground-breaking new Paris show on the representation of people of colour in art.
A Canadian artist is building a wall of cheese near the border that separates the US and Mexico in Tecate, California, as a way of denouncing the "waste" represented by the barrier that American President Donald Trump wants to construct.
Chinese artist Ai Weiwei unveiled a new installation in Mexico that tells the story of 43 students likely massacred five years ago in a case that exposed government stonewalling and complicity in abuses, a frequent theme for the dissident artist.
The high-tech future of green jobs and the Gandhian virtue of the dignity of work meld their messages on a six-storey high mural commemorating the 150th birth anniversary of Mahatma Gandhi and the centenary of the International Labour Organisation (ILO).
Actress Kiara Advani dazzled the opening show of India Couture Week (ICW) 2019, wearing a red-coloured quintessential bridal lehenga.
A stone gargoyle, a gilded fairy, a cast-bronze king and other fantastical statues came alive in Belgium as street artists showed off their creations at Europe's biggest "living statue" festival.
Veteran rocker Mick Jagger will return to the silver screen at the Venice film festival in September for the premiere of art-world thriller "The Burnt Orange Heresy", alongside Donald Sutherland.