In this photo shows outgoing President Jimmy Morales (centre) evacuated by police agents in Guatemala City. AP

Protesters surrounded outgoing Guatemalan President Jimmy Morales late on Tuesday, throwing eggs at him and his vice president as they sought to take up new posts that bring immunity from prosecution, just hours after leaving office.

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Protesters yelling "Murderer" jostled Morales' police detail and let off a loud firework as he tried to reach a hotel that is the temporary headquarters of Central America's regional parliament, a Reuters witness said.

A woman hits a paper doll of outgoing President Jimmy Morales in Guatemala City, on Tuesday. AP

Moments later he was stuck by a plastic object and the eggs.

Morales and former Vice President Jafeth Cabrera were on their way to be sworn in as new members of the regional parliament when protesters blocked their entry to the hotel.

Until they take their oaths of office in the new roles, they are exposed to the possibility of arrest.

Morales was immune from prosecution while president. He has previously been investigated over accusations of campaign finance violations.

Reuters